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J. Miller, W. Charlton, and R. Steiner, "Investigation of Trace Uranium in Biological Matrices," INMM 54th Annual Meeting, 14-18 July 2013, Palm Desert, California, USA.


With the use of nuclear technology spreading, there is a growing need to monitor workers for occupational exposures to ensure their heath and safety. Methods for monitoring Uranium exposures have been implemented for the entire lifetime of the nuclear industry; however, using recent technologies, these methods can be improved. This work is an implementation of an electrochemical preconcentration process originally posited and developed at Oak Ridge National Laboratory for use as a preprocessing to increase both efficiency and sensitivity in conjunction with Inductively Coupled Plasma Mass Spectrometry. The specific application of this work is for detection of Uranium in urine for individuals exposed during normal industry exposures as well as background exposures. This work will discuss the feasibility of using this method for preparing samples for analysis as well as the initial methodology developments and observations from adaptation of the technique for use with urine samples. Initial computer modeling suggests that this technique will be effective for detecting chronic exposures of Uranium; however, it will not be as effective in detecting short term acute exposures. LA-UR: 'LA-UR-12-21937' Related LA-UR's: 11-02046


Associated Project(s):

  • Measurement of Uranium in Bio Matrices for Nuclear Forensic Purposes

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